Development of iPSC-Derived Cellular Models from Patients with Spinal Muscular Atrophy and In Vitro Phenotypic Characterization Using iPSC-Derived Cells
Laboratory: : Institut NeuroMyoGène, Laboratoire Physiopathologie et Génétique du Neurone et du Muscle
Research team: Equipe Schaeffer
Role of TGF-beta signalling in connective tissue precursors for skeletal muscle patterning
Laboratory: Institut de Génomique Fonctionnelle de Lyon (IGFL / ENS Lyon)
Research team: “Developmental and Evolutionary Histories of Vertebrates” (DEHV)
Laboratory: Institut NeuroMyoGène - Physiopathologie et Génétique du Neurone et du Muscle (PGNM)
Research team: Stem cell environment and skeletal muscle homeostasis
Role of TGF-beta signalling in connective tissue precursors for skeletal muscle patterning
Laboratory: Institut de Génomique Fonctionnelle de Lyon (IGFL / ENS Lyon), CNRS UMR 5242
Research team: “Developmental and Evolutionary Histories of Vertebrates” (DEHV)
Deciphering the microtubule network re-organization during muscle fiber formation using “Live-SuperResolution Microscopy” in healthy and pathological conditions
Laboratory: Pathophysiology and genetics of neuron and muscle (PGNM)
Research team: Muscle Nuclear & Cytoskeleton Architecture (MNCA)
Control of the degenerative cartilage through the histone modifying enzyme lsd-1
Laboratory: Tissue Biology and Therapeutic Engineering Laboratory (LBTI), CNRS UMR 5305
Research objective:
Our project aims at deciphering the epigenetic signaling exerted by the histone modifying enzyme Lsd-1 in articular cartilage. The interplay with inflammatory pathway and metabolism will be analysed in the context of degenerative joint disease such as osteoarthritis (OA).
BFstretch project: “Assessment of mechanical behaviour in the two heads of the biceps femoris muscle during passive knee motion at different hip angles”
Laboratory: Laboratoire Interuniversitaire de Biologie de la Motricité, UR 7424.
Deciphering microtubule network re-organization during
muscle fiber formation using “Live-Super-Resolution
Microscopy” in healthy and pathological conditions
Laboratory: Pathophysiology and genetics of neuron and muscle (PGNM)
CNRS/UCBL1 UMR 5261 - INSERM U1315