As we have launched a call for project in September 2024, we have funded the following projects
Anaelle SARRAZIN, is enrolled in a Master 2 in biomedical engineering (Medical imaging and surgical robotics) at Télécom Physique Strasbourg (University of Strasbourg). She received a student award for her research in medical image processing for the quantification of postoperative success of total ankle prosthesis placement according to the chosen method of constructing the preoperative plan (recalibrated CT vs. CBHR).
– Internship topic: total ankle prosthesis placement according to the chosen method of constructing the preoperative plan
– Supervisor: Yoann LAFON, Head of Research at LBMC
Trang Ngan GIANG, obtained a Bachelor in Biology in 2023 from the Vietnam National University (HUS) in Hanoi. Since 2024, she is enrolled in a M2 master degree in Cancer Bioengineering at University Lyon 1. She has been a Research Intern at Vinmec Research Institute of Stem Cell and Gene Technology in Hanoi from May 2022 to July 2024 where she worked of innovative therapeutic approaches based on stem cells.
– Internship topic: Photothermal and phototherapeutic effects induced by nanozymes to facilitate the penetration of anti-cancer agents
– Supervisor: Virginie Monnier, Associate Professor from Ecole Centrale de Lyon, INL
– Aim of the internship: This M2 internship will concern the therapy of pancreatic cancer which is a challenge for oncologists because of the weak efficacy of chemotherapy. It is mainly due to the limited diffusion of drugs towards the tumor, because of the particularly dense tumor microenvironment. We will use here gold-based nanoparticles able to generate both photothermal and photodynamic effects in order to weaken the pancreatic tumor environment and to facilitate the penetration of anti-cancer agents.
Driss BOUSHAIB, has studied in France after a baccaleureat in Morocco, he is graduated from the university of Toulon where he obtained a bachelor in physics and chemistry. He enrolled in a master degree in “Applied Physics and Physics Engineering”, option “Spectroscopies, engineering and instrumentation” at the university of Reims Champagne- Ardenne. He has research interest in the field of applied physics and instrumentation and also in experimental data analyses for which he has knowledge in different languages (python, matlab, comsol Multiphysics…). During his last internship in the research in Nanoscience lab he has acquired skills in Atomic Force Microscopy (AFM), the technique and the instrument) by participating to the calibration of the instrument on many different surfaces.
– Internship topic: AFM Force measurements on Polymer brushes on Nanocarriers for Medical Device Improvement
– Supervisor: Magali Phaner, Professor Ecole Centrale de Lyon, INL
– Aim of the internship: Characterization by Atomic Force Microscopy (AFM) of lipid nanocapsules and polymer brushes for nanomedecine applications (drug delivery, antifouling properties). The project includes AFM force measurements in solution and the development of a model to interpret the mechanical and chemical forces involved.
Adria SAOUDI, obtained her Licence degree in Chemistry from University Lyon 1 in 2023. She is currently enrolled in Inorganic Chemistry Master degree at University Lyon 1.
– Internship topic: identification of new chelating molecules towards metal ions for vectorized internal therapy
– Supervisor: Emmanuelle Laurenceau, Head of the Health Engineering master’s degree, INL
– Aim of the internship: collaborate between INL, MATEIS and CRCL, funded by Graduate School of Medical Device Engineering, on the identification of new chelating molecules towards metal ions for vectorized internal therapy. The chelating affinity between small synthesized molecules and metal ions will be explored using Surface Plasmon Resonance analysis.
Mateo PAIN, is a Computer Engineering student at CPE Lyon. He is still enrolled in the program.
– Internship topic: A Generative Prompt Model for 3D Synthetic Healthy Brain MRI with Multiple Sclerosis Lesion Augmentation
– Supervisor: Chantal Muller, Associate Professor, CREATIS
– Aim of the internship: this project aims at developing deep learning models to segment some new multiple sclerosis lesions from IRM FLAIR data. At the end of the project, a tool to help diagnose and track the disease should be created.
Hélène HEMBERT, has graduated from the Lyon School of Chemistry and Electronics (CPE Lyon), As an R&D chemical engineer, she has worked in various chemical specialities companies to develop new polymeric materials and processes, and has managed as a scientific consultant the Research Tax Credit and R&D organizations of industrial companies. She also has developed new tools and collaborative projects in sustainable innovation or the Frenhc outdoor sports equipments companies. She is enrolled in a master degree in Medical Device Engineering at Polytech Lyon to work as a R&D project manageer in the implantable medical devices industry thereafter. She has research interest in implantable medical devices, specifically biodegradable ones, in orthopaedics and cardialogics as well as in tissue regeneration.
– Internship topic: Mechanical characterization and preclinical evaluation of a mini-invasive dental implant
– Supervisor: Rémy GAUTHIER, Research fellow, CREATIS
– Aim of the internship: Research Tax Credit and R&D organizations of industrial companies. She also has developed new tools and collaborative projects in sustainable innovation or the Frenhc outdoor sports equipments companies. She is enrolled in a master degree in Medical Device Engineering at Polytech Lyon to work as a R&D project manageer in the implantable medical devices industry thereafter. She has research interest in implantable medical devices, specifically biodegradable ones, in orthopaedics and cardialogics as well as in tissue regeneration.
Lucie DRAPIER, is enrolled in a master degree in engineering at École Centrale de Lyon. She has a research interest in biomedical engineering and has already taken part in two projects in related fields.
– Internship topic: Development of a cardiac biomechanical simulator for the optimization of cardiological medical devices
– Supervisor: Rémy GAUTHIER, Research fellow, CREATIS
– Aim of the internship: The mitral valve plays a crucial role in directing blood flow from the left atrium to the left ventricle, but damage can lead to regurgitation, necessitating valve replacement. To minimize animal testing in prosthetic valve development, we aim to create a cardiac simulator that mimics in vivo conditions using a pulsatile pump, sensors, and a porcine heart model. This device will help evaluate the mitral valve performance while addressing ethical concerns in biomedical research.
Prince NDOUMBE, is enrolled in the Master in Inorganic Chemistry at the Universite Claude Bernard Lyon 1. He has research interests in organic and inorganic synthesis and in nanomaterials.
– Internship topic: Development of an antimicrobial hydrogel to coat urinary catheter
– Aim of the internship: he objective of this project is to develop an antimicrobial hydrogel to coat urinary catheter to avoid nosocomial infections. This hydrogel will be used on short term and long-term catheter. Based on first promising results at laboratory showing the antimicrobial properties of low cost, lubricant and cytocompatible hydrogel, we would like to show that these hydrogels can be used to coat urinary catheter to reduce infections. The results of this project will benefit a wide community of patients, biomaterial scientists and industries.
As we have launched a call for project in September 2023, we have funded the following projects
Enkhmaa MUNKHSAIKHAN, graduated from a Bachelor of Engineering, Nano science and Engineering at the National University of Mongolia. She is currently enrolled in a Master in Nanochemistry at Université Grenoble Alpes.
She obtained several prizes:
Second Place, Technology in the Advancement of Science (2022)
Best Poster Award, First International Conference of Natural and Biological Resources Technologies in Mongolia (2022)
Third Place, Khureltogoot (2022)
Her medical device research interests revolve around nanoparticles.
– Internship topic: Gold based nanoparticles for photo induced hyperthermia on pancreatic tumor environment to facilitate the penetration of anti-cancer agents.
– Supervisor: Virginie MONNIER, Associate Professor from Ecole Centrale de Lyon, INL
– Aim of the internship: this M2 internship concerned the therapy of pancreatic cancer which is a challenge for oncologists because of the weak efficacy of chemotherapy. It is mainly due to the limited diffusion of drugs towards the tumor, because of the particularly dense tumor microenvironment. Gold-based nanoparticles were used to generate a photothermal effect in order to weaken the pancreatic tumor environment and to facilitate the penetration of anti-cancer agents.
Elvy Greg Bienvenu KEBILA MOUTSINGA, graduated from a Master 2 Cancer of Bioengineering at the University Claude Bernard Lyon 1.
His medical device research interests revolve around nanotechnology
– Internship topic: use of an electro-deformation platform to obtain the mechanical signature of commercial AML cells in relation to their resistance to treatment.
– Supervisor: Magalie Faivre, CNRS Researcher at the Institut des Nanotechnologies de Lyon
– Aim of the internship: acute myeloid leukemia (AML) develops in the bone marrow from stem cells in particular, which are transformed into leukemic cells that proliferate and cause the production of normal hematopoietic cells to dry up. The cellular transition towards a leukemic phenotype of stem cells is accompanied by various mechanical modifications of the tumor environment, which can in return affect the intrinsic cellular rigidity of leukemia cells through a reciprocal mechanical response. This internship aims to evaluate the use of an electro-deformation platform to obtain the mechanical signature of commercial AML cells in relation to their resistance to treatment, with a much higher throughput than conventional methods.
Rémi BADEL, graduated from a master’s degree in computer science (Advanced Computing and Applications) at the University of Franche-Comté. He graduated from a master’s degree in Computer Science (Advanced Computing and Applications) at the Université of Franche-Comté.
His medical device research interests revolve around Medical Imaging.
– Internship topic: Removal of ultrasound artefacts using neural networks
– Supervisor: Fabien MILLIOZ, Associate Professor at the CREATIS laboratory
– The aim of this internship is twofold: first, used an existing simulator to create ultrasound images of better quality than one cat obtain with physical probes,
and simulated the associated ultrasound signal obtain with a realistic probe;
second, trained a neural network to reconstruct the better-than-physics ultrasound images from the realistic simulated acquisitions, in order to remove some artifacts automatically, and improved global quality of the acquisitions.
Loic DEMORE, graduated from a Biomedical Engineering master’s degree at the INP Phelma Grenoble.
His medical device research interests revolve around Medical Imaging.
– Internship topic: Development of Advanced MRI Techniques for the Longitudinal Study of Multiple Sclerosis
– Supervisor: Carole FRINDEL, Associate Professor at INSA Lyon
– Aim of the internship: developed a new MRI imaging technique to identify areas of the brain affected by oxygen deficiency during stroke, inspired by methods used in positron emission tomography. The aim was to create a machine-learning model that shows areas of the brain where oxygen metabolism was reduced (“metabolic penumbra”), using specific maps derived from T2* perfusion MRI. This new model was then compared with current MRI methods used in clinical routine
Yosra CHRIGUI, graduated from a Master professionnel en Métrologie et Ingénierie de la Qualité in 2023 at the Institut National des Sciences Appliquées et de Technologies. She graduated from the Master in Medical Device Engineering in 2024 at Université Claude Bernard Lyon 1.
Her medical device research interests revolve around biosensors.
– Internship topic: development of a biosensor to test breast cancer’s saliva: medical application
– Supervisor: Abdelhamid ERRACHID EL SALHI, Professor at the Institut des Sciences Analytiques
– Aim of the internship: produce a handy and easy to use medical application. This new method of cancer detection consists in developing an electrochemical biosensor able to detect breast cancer thanks to salivary biomarkers.