Musculo-Skeletal system, Locomotion, Exercise – Graduate Plus

Musculo-Skeletal system, Locomotion, Exercise

The overall purpose of the MuSkLE (Musculo-Skeletal system, Locomotion & Exercise) consortium is to set up a network of close to 600 scientists (18 teams and 8 institutes) and clinicians in Saint-Etienne and Lyon specialized in the study of the musculoskeletal system, locomotion and exercise.

MuSkLE aims at identifying the impact of physical exercise, in particular locomotor activities, on the entire musculoskeletal system in different physiological (e.g., athletes, nutrition) and pathophysiological contexts (e.g., osteoporosis, neuromuscular diseases, cancer, inflammatory rheumatism, aging…). Indeed, exercise has been consistently described as a ‘polypill’ to prevent and care multiple diseases but the posology still has to be defined and individualized.

The objective is to break down the borders between fields to propose a true interdisciplinary research on this theme from a molecular to an integrative level, using different models (cell, drosophila, zebrafish, rodent, athlete, patient…).

This original and multi-scale approach (i.e., cellular, tissue, whole organ) will allow to:

Improve our understanding of several diseases
Study the role of physical exercise and locomotion in their management,
Understand the plasticity of this system in response to exercise,
Understand the plasticity of this system in response to exercise,

The MuSkLE consortium is coordinated by Dr Rémi Mounier and Prof. Vincent Pialoux.

2025-2026: Call for Excellence Scholarships for Master 2 students

We are pleased to announce the launching of the Excellence Scholarship Campaign for Masters students who wish to attend one of the masters of the MuSkLE Graduate Programme.

Submissions open: November 6^th, 2024
Deadline for applications: January 31^st 2025

MuSkLE: Summer school

Save the date: from June 01 to June 06, 2025

We welcome Bachelor (in priority) and Master students in molecular biology, cell biology, medicine, physiotherapy, physiology and exercise science interested in research on the musculo-skeletal system.

Application dealine: January 13, 2025

MUSKLE: Research Internship - M2

Phenotype of canine chondrocytes across age and condition of hip and stifle joints

MUSKLE: Research Internship - M2

Effect on bone of physical training and nutritional supplementation in microgravity analog model in rat.

MUSKLE: Research Internship - M2

Control of the degenerative cartilage through the histone modifying enzyme lsd-1

MUSKLE: Research Internship - M2

Evaluation of isolated muscle functional capabilities under environmental stress using the innovative FOVE ergometer.

MUSKLE: Research Internship - M2

Extracellular matrix function in motor nerve regeneration in zebrafish

MUSKLE: Research Internship - M2

Building and maintaining the architecture of the locomotor system: from genes to function.

MUSKLE: Research Internship - M2

Impact of inflammation in the composition and function of skeletal muscle-released extracellular vesicles on macrophages

MUSKLE: Research Internship - M2

Role of PHF2 lysine demethylase in the lipid metabolism regulation of Muscle stem cell fate.

MUSKLE: Research Internship - M2

Striated skeletal muscle resistance to cancer metastasis

MUSKLE: Research Internship - M2

BFstretch project: “Assessment of mechanical behaviour in the two heads of the biceps femoris muscle during passive knee motion at different hip angles”

MUSKLE: Research Internship - M2

Influence of transient vibrations on fatigue and muscle damage

MUSKLE: Research Internship - M2

Mechanical loading and immune cells recruitment in arthritis

MUSKLE: Research Internship - M2

Effects of perceived shoulder dysfunction on the biomechanics of physical performance tests for upper limbs in athletes

MUSKLE: Research Internship - M2

Development of biomimetic tools for cartilage tissue engineering

MUSKLE: Research Internship - M2

Deciphering microtubule network re-organization during muscle fiber formation using “Live-Super-Resolution Microscopy” in healthy and pathological conditions

Fields

Musculo-Skeletal system

Biology

Biomechanics

Health

Kinesiology

Medicine

Physiology

A Programme from Master to PhD

Upon entering the Graduate+ Initiatives Master programme, students will work closely with faculty and researchers to build their academic project. Each student will be assigned an academic advisor and will be actively involved in research activities throughout the programme.

MASTER
DOCTORAL SCHOOLS
RESEARCH

Select from one of our Master's programmes and map out your own academic journey. You can customise your path according to your interests and objectives with a diverse range of Master's options.

Master in Integrative Biology and Physiology

M2 : Environmental and Muscle Physiology
M2 : Régulations cardiovasculaires, métaboliques et nutritionnelles - Cardiovascular, Metabolic, and Nutritional Regulations
M2 : Recherche animale pré-clinique et clinique - Pre-clinical and Clinical Animal Research
M2 : Musculo-Skeletal system, Locomotion, Exercise - Musculo-Skeletal System, Locomotion, Exercise

STAPS Master's: Training and Optimization of Sports Performance

M2 : Sciences du Mouvement et Santé - Movement Sciences and Health
M2 : Préparation du sportif: aspects physiques, mentaux et ré-atlhétisation - Athlete Preparation: Physical, Mental, and Re-athletization Aspects
M2 : Musculo-Skeletal system, Locomotion, Exercise

Master in Mechanical Engineering

M2 : Biomécanique - Biomechanics
M2 : Musculo-Skeletal system, Locomotion, Exercise

Master in Health Engineering

M2 : Recherche et réhabilitation du handicap moteur - Research and Rehabilitation of Motor Disability

Doctoral research is conducted in a partner laboratory at Graduate +. The training takes place in a doctoral school.

Associated doctoral schools:

Ecole Doctorale Interdisciplinaire Sciences Santé (EDISS ED 205) - Health Sciences
Ecole Doctorale Sciences, Ingénierie, Santé (SIS ED 488) - Science, Engineering and Health
Ecole Doctorale Biologie Moléculaire Intégrative et Cellulaire (BMIC ED 340) - Integrative and Cellular Molecular Biology
Ecole Doctorale Mécanique, énergétique, génie civil, acoustique (MEGA ED 162) - Mechanics, Energy, Civil Engineering and Acoustics

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Partner laboratories

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Partner Laboratories

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Students

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PhD Students

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